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Possible Mechanisms by which Stefin B could Regulate Proteostasis and Oxidative Stress
Human stefin B is a protease inhibitor from the family of cystatins. It was reported that it forms oligomers in cells. We have shown that it has a role in cell’s response to misfolded proteins. We also have shown that its oligomers bind amyloid-beta (Aβ). Here, we discuss ways, how stefin B could re...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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MDPI
2019
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6357131/ https://www.ncbi.nlm.nih.gov/pubmed/30669344 http://dx.doi.org/10.3390/cells8010070 |