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InTAD: chromosome conformation guided analysis of enhancer target genes

BACKGROUND: High-throughput technologies for analyzing chromosome conformation at a genome scale have revealed that chromatin is organized in topologically associated domains (TADs). While TADs are relatively stable across cell types, intra-TAD activities are cell type specific. Epigenetic profiling...

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Detalles Bibliográficos
Autores principales: Okonechnikov, Konstantin, Erkek, Serap, Korbel, Jan O., Pfister, Stefan M., Chavez, Lukas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6357397/
https://www.ncbi.nlm.nih.gov/pubmed/30704404
http://dx.doi.org/10.1186/s12859-019-2655-2