Helicobacter pylori-controlled c-Abl localization promotes cell migration and limits apoptosis

BACKGROUND: Deregulated c-Abl activity has been intensively studied in a variety of solid tumors and leukemia. The class-I carcinogen Helicobacter pylori (Hp) activates the non-receptor tyrosine kinase c-Abl to phosphorylate the oncoprotein cytotoxin-associated gene A (CagA). The role of c-Abl in Ca...

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Detalles Bibliográficos
Autores principales: Posselt, Gernot, Wiesauer, Maria, Chichirau, Bianca E., Engler, Daniela, Krisch, Linda M., Gadermaier, Gabriele, Briza, Peter, Schneider, Sabine, Boccellato, Francesco, Meyer, Thomas F., Hauser-Kronberger, Cornelia, Neureiter, Daniel, Müller, Anne, Wessler, Silja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6357398/
https://www.ncbi.nlm.nih.gov/pubmed/30704478
http://dx.doi.org/10.1186/s12964-019-0323-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6357398/
https://www.ncbi.nlm.nih.gov/pubmed/30704478
http://dx.doi.org/10.1186/s12964-019-0323-9

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