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Docetaxel-loaded human serum albumin (HSA) nanoparticles: synthesis, characterization, and evaluation

BACKGROUND: Docetaxel (DTX) is an anticancer drug that is currently formulated with polysorbate 80 and ethanol (50:50, v/v) in clinical use. Unfortunately, this formulation causes hypersensitivity reactions, leading to severe side-effects, which have been primarily attributed to polysorbate 80. METH...

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Detalles Bibliográficos
Autores principales: Qu, Na, Sun, Yating, Li, Yujing, Hao, Fei, Qiu, Pengyu, Teng, Lesheng, Xie, Jing, Gao, Yin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6357434/
https://www.ncbi.nlm.nih.gov/pubmed/30704488
http://dx.doi.org/10.1186/s12938-019-0624-7