Gene editing of the multi-copy H2A.B gene and its importance for fertility

BACKGROUND: Altering the biochemical makeup of chromatin by the incorporation of histone variants during development represents a key mechanism in regulating gene expression. The histone variant H2A.B, H2A.B.3 in mice, appeared late in evolution and is most highly expressed in the testis. In the mou...

Descripción completa

Detalles Bibliográficos
Autores principales: Anuar, Nur Diana, Kurscheid, Sebastian, Field, Matt, Zhang, Lei, Rebar, Edward, Gregory, Philip, Buchou, Thierry, Bowles, Josephine, Koopman, Peter, Tremethick, David J., Soboleva, Tatiana A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6357441/
https://www.ncbi.nlm.nih.gov/pubmed/30704500
http://dx.doi.org/10.1186/s13059-019-1633-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6357441/
https://www.ncbi.nlm.nih.gov/pubmed/30704500
http://dx.doi.org/10.1186/s13059-019-1633-3

Ejemplares similares