A subgroup of microRNAs defines PTEN-deficient, triple-negative breast cancer patients with poorest prognosis and alterations in RB1, MYC, and Wnt signaling

BACKGROUND: Triple-negative breast cancer (TNBC) represents a heterogeneous group of ER- and HER2-negative tumors with poor clinical outcome. We recently reported that Pten-loss cooperates with low expression of microRNA-145 to induce aggressive TNBC-like lesions in mice. To systematically identify...

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Detalles Bibliográficos
Autores principales: Wang, Dong-Yu, Gendoo, Deena M. A., Ben-David, Yaacov, Woodgett, James R., Zacksenhaus, Eldad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6357448/
https://www.ncbi.nlm.nih.gov/pubmed/30704524
http://dx.doi.org/10.1186/s13058-019-1098-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6357448/
https://www.ncbi.nlm.nih.gov/pubmed/30704524
http://dx.doi.org/10.1186/s13058-019-1098-z

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