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A pilot study on sperm DNA damage in β-thalassemia major: is there a role for antioxidants?

Excess iron deposition in patients with beta thalassemia major (BTM) causes excess free radical formation, damages the hypothalamic pituitary testicular axis and production of sperms with DNA defects. As antioxidants were reported to improve fertility in healthy males; their effectiveness to improve...

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Detalles Bibliográficos
Autores principales: Elsedfy, Heba, Sanctis, Vincenzo De, Ahmed, Alaa Youssef, Mohamed, Noha Refaat, Arafa, Mohamed, Elalfy, Mohsen Saleh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mattioli 1885 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6357624/
https://www.ncbi.nlm.nih.gov/pubmed/29633742
http://dx.doi.org/10.23750/abm.v89i1.6836