Subculturing cells have no effect on CRISPR/Cas9‐mediated cleavage of UL30 gene in pseudorabies virus

CRISPR/Cas9‐mediated genome editing can inhibit virus infection by targeting the conserved regions of the viral genomic DNA. Unexpectedly, we found previously that pseudorabies virus (PRV) could escape from CRISPR/Cas9‐mediated inhibition. In order to elucidate whether the escape of PRV from Cas9‐me...

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Detalles Bibliográficos
Autores principales: Ren, Lin‐zhu, Peng, Zhi‐yuan, Ouyang, Ting, Liu, Xiao‐hui, Chen, Xin‐rong, Ye, Li, Fan, Jun‐wen, Ouyang, Hong‐sheng, Pang, Da‐xin, Bai, Jie‐ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6357676/
https://www.ncbi.nlm.nih.gov/pubmed/30891550
http://dx.doi.org/10.1002/ame2.12006

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6357676/
https://www.ncbi.nlm.nih.gov/pubmed/30891550
http://dx.doi.org/10.1002/ame2.12006

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