Tetrahydroquinoxalines induce a lethal evisceration phenotype in Haemonchus contortus in vitro

In the present study, the anthelmintic activity of a human tyrosine kinase inhibitor, AG-1295, and 14 related tetrahydroquinoxaline analogues against Haemonchus contortus was explored. These compounds were screened against parasitic larvae - exsheathed third-stage (xL3) and fourth-stage (L4) - using...

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Detalles Bibliográficos
Autores principales: Jiao, Yaqing, Preston, Sarah, Garcia-Bustos, Jose F., Baell, Jonathan B., Ventura, Sabatino, Le, Thuy, McNamara, Nicole, Nguyen, Nghi, Botteon, Antony, Skinner, Cameron, Danne, Jill, Ellis, Sarah, Koehler, Anson V., Wang, Tao, Chang, Bill C.H., Hofmann, Andreas, Jabbar, Abdul, Gasser, Robin B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6357688/
https://www.ncbi.nlm.nih.gov/pubmed/30690282
http://dx.doi.org/10.1016/j.ijpddr.2018.12.007

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6357688/
https://www.ncbi.nlm.nih.gov/pubmed/30690282
http://dx.doi.org/10.1016/j.ijpddr.2018.12.007

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