POLE-mutated clear cell cervical cancer associated with in-utero diethylstilbestrol exposure

We report an extraordinary case of a woman, exposed to diethylstilbestrol in utero, who developed clear cell adenocarcinoma of the cervix with a concurrent polymerase-Ɛ (POLE) somatic mutation. The tumor exhibited the classic phenotypic characteristics of POLE-mutated tumors originating from other o...

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Detalles Bibliográficos
Autores principales: Lee, Elizabeth K., Lindeman, Neal I., Matulonis, Ursula A., Konstantinopoulos, Panagiotis A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6357694/
https://www.ncbi.nlm.nih.gov/pubmed/30733993
http://dx.doi.org/10.1016/j.gore.2019.01.012

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6357694/
https://www.ncbi.nlm.nih.gov/pubmed/30733993
http://dx.doi.org/10.1016/j.gore.2019.01.012

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