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POLE-mutated clear cell cervical cancer associated with in-utero diethylstilbestrol exposure

We report an extraordinary case of a woman, exposed to diethylstilbestrol in utero, who developed clear cell adenocarcinoma of the cervix with a concurrent polymerase-Ɛ (POLE) somatic mutation. The tumor exhibited the classic phenotypic characteristics of POLE-mutated tumors originating from other o...

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Detalles Bibliográficos
Autores principales:	Lee, Elizabeth K., Lindeman, Neal I., Matulonis, Ursula A., Konstantinopoulos, Panagiotis A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2019
Materias:	Case Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6357694/ https://www.ncbi.nlm.nih.gov/pubmed/30733993 http://dx.doi.org/10.1016/j.gore.2019.01.012

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