A Golgi-targeting fluorescent probe for labile Fe(ii) to reveal an abnormal cellular iron distribution induced by dysfunction of VPS35

Iron is involved in numerous physiologically essential processes in our body. However, excessive iron is a pathogenic factor in neurodegenerative diseases, causing aberrant oxidative stress. Divalent metal transporter 1 (DMT1) acts as a primary transporter of Fe(ii) ions. The intracellular delivery...

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Detalles Bibliográficos
Autores principales: Hirayama, Tasuku, Inden, Masatoshi, Tsuboi, Hitomi, Niwa, Masato, Uchida, Yasuhiro, Naka, Yuki, Hozumi, Isao, Nagasawa, Hideko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2018
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6357701/
https://www.ncbi.nlm.nih.gov/pubmed/30809369
http://dx.doi.org/10.1039/c8sc04386h

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6357701/
https://www.ncbi.nlm.nih.gov/pubmed/30809369
http://dx.doi.org/10.1039/c8sc04386h

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