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A Golgi-targeting fluorescent probe for labile Fe(ii) to reveal an abnormal cellular iron distribution induced by dysfunction of VPS35
Iron is involved in numerous physiologically essential processes in our body. However, excessive iron is a pathogenic factor in neurodegenerative diseases, causing aberrant oxidative stress. Divalent metal transporter 1 (DMT1) acts as a primary transporter of Fe(ii) ions. The intracellular delivery...
Autores principales: | Hirayama, Tasuku, Inden, Masatoshi, Tsuboi, Hitomi, Niwa, Masato, Uchida, Yasuhiro, Naka, Yuki, Hozumi, Isao, Nagasawa, Hideko |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Royal Society of Chemistry
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6357701/ https://www.ncbi.nlm.nih.gov/pubmed/30809369 http://dx.doi.org/10.1039/c8sc04386h |
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