Inhibition of HBV Transcription From cccDNA With Nitazoxanide by Targeting the HBx–DDB1 Interaction

BACKGROUND & AIMS: Hepatitis B virus (HBV) infection is a major health concern worldwide. Although currently used nucleos(t)ide analogs efficiently inhibit viral replication, viral proteins transcribed from the episomal viral covalently closed circular DNA (cccDNA) minichromosome continue to be...

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Detalles Bibliográficos
Autores principales: Sekiba, Kazuma, Otsuka, Motoyuki, Ohno, Motoko, Yamagami, Mari, Kishikawa, Takahiro, Suzuki, Tatsunori, Ishibashi, Rei, Seimiya, Takahiro, Tanaka, Eri, Koike, Kazuhiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6357790/
https://www.ncbi.nlm.nih.gov/pubmed/30704981
http://dx.doi.org/10.1016/j.jcmgh.2018.10.010

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6357790/
https://www.ncbi.nlm.nih.gov/pubmed/30704981
http://dx.doi.org/10.1016/j.jcmgh.2018.10.010

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