Epidermal Growth Factor Reverses the Inhibitory Effects of the Bisphosphonate, Zoledronic Acid, on Human Oral Keratinocytes and Human Vascular Endothelial Cells In Vitro via the Epidermal Growth Factor Receptor (EGFR)/Akt/Phosphoinositide 3-Kinase (PI3K) Signaling Pathway

BACKGROUND: Medication-related osteonecrosis of the jaw (MRONJ) is due to the direct effects of drug toxicity and the effects on angiogenesis. The aims of this study were to evaluate the effects of treatment with the bisphosphonate, zoledronic acid, on human oral keratinocytes (HOKs) and human umbil...

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Detalles Bibliográficos
Autores principales: Wang, Qizhang, Liu, Jiyuan, Guo, Ting, Liu, Dazhong, Pan, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2019
Materias:
Lab/In Vitro Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6357820/
https://www.ncbi.nlm.nih.gov/pubmed/30675875
http://dx.doi.org/10.12659/MSM.911579

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6357820/
https://www.ncbi.nlm.nih.gov/pubmed/30675875
http://dx.doi.org/10.12659/MSM.911579

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