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Phillygenin Exerts In Vitro and In Vivo Antitumor Effects in Drug-Resistant Human Esophageal Cancer Cells by Inducing Mitochondrial-Mediated Apoptosis, ROS Generation, and Inhibition of the Nuclear Factor kappa B NF-κB Signalling Pathway

BACKGROUND: Esophageal cancer causes considerable mortality and is ranked as the 6(th) most prevalent type of cancer across the world. At present, there is no effective esophageal cancer chemotherapy without adverse effects. Moreover, emergence of drug resistance among cancer is another obstacle in...

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Detalles Bibliográficos
Autores principales: He, Jiantao, Wei, Wei, Yang, Qingbo, Wang, Yiling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6357824/
https://www.ncbi.nlm.nih.gov/pubmed/30681987
http://dx.doi.org/10.12659/MSM.913138