Intestine‐Specific Overexpression of Carboxylesterase 2c Protects Mice From Diet‐Induced Liver Steatosis and Obesity

Murine hepatic carboxylesterase 2c (Ces2c) and the presumed human ortholog carboxylesterase 2 (CES2) have been implicated in the development of nonalcoholic fatty liver disease (NAFLD) in mice and obese humans. These studies demonstrated that Ces2c hydrolyzes triglycerides (TGs) in hepatocytes. Inte...

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Detalles Bibliográficos
Autores principales: Maresch, Lisa Katharina, Benedikt, Pia, Feiler, Ursula, Eder, Sandra, Zierler, Kathrin A., Taschler, Ulrike, Kolleritsch, Stephanie, Eichmann, Thomas O., Schoiswohl, Gabriele, Leopold, Christina, Wieser, Beatrix I., Lackner, Caroline, Rülicke, Thomas, van Klinken, Jan, Kratky, Dagmar, Moustafa, Tarek, Hoefler, Gerald, Haemmerle, Guenter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6357831/
https://www.ncbi.nlm.nih.gov/pubmed/30766961
http://dx.doi.org/10.1002/hep4.1292

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6357831/
https://www.ncbi.nlm.nih.gov/pubmed/30766961
http://dx.doi.org/10.1002/hep4.1292

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