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Intestine‐Specific Overexpression of Carboxylesterase 2c Protects Mice From Diet‐Induced Liver Steatosis and Obesity
Murine hepatic carboxylesterase 2c (Ces2c) and the presumed human ortholog carboxylesterase 2 (CES2) have been implicated in the development of nonalcoholic fatty liver disease (NAFLD) in mice and obese humans. These studies demonstrated that Ces2c hydrolyzes triglycerides (TGs) in hepatocytes. Inte...
Autores principales: | Maresch, Lisa Katharina, Benedikt, Pia, Feiler, Ursula, Eder, Sandra, Zierler, Kathrin A., Taschler, Ulrike, Kolleritsch, Stephanie, Eichmann, Thomas O., Schoiswohl, Gabriele, Leopold, Christina, Wieser, Beatrix I., Lackner, Caroline, Rülicke, Thomas, van Klinken, Jan, Kratky, Dagmar, Moustafa, Tarek, Hoefler, Gerald, Haemmerle, Guenter |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6357831/ https://www.ncbi.nlm.nih.gov/pubmed/30766961 http://dx.doi.org/10.1002/hep4.1292 |
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