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EGFR deficiency leads to impaired self-renewal and pluripotency of mouse embryonic stem cells
BACKGROUND: Self-renewal and pluripotency are considered as unwavering features of embryonic stem cells (ESCs). How ESCs regulate the self-renewal and differentiation is a central question in development and regenerative medicine research. Epidermal growth factor receptor (EGFR) was identified as a...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
PeerJ Inc.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6357870/ https://www.ncbi.nlm.nih.gov/pubmed/30713819 http://dx.doi.org/10.7717/peerj.6314 |