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Mst1 inhibition attenuates non-alcoholic fatty liver disease via reversing Parkin-related mitophagy

Obesity-related non-alcoholic fatty liver disease (NAFLD) is connected with mitochondrial stress and hepatocyte apoptosis. Parkin-related mitophagy sustains mitochondrial homeostasis and hepatocyte viability. However, the contribution and regulatory mechanisms of Parkin-related mitophagy in NAFLD ar...

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Detalles Bibliográficos
Autores principales: Zhou, Tao, Chang, Ling, Luo, Yi, Zhou, Ying, Zhang, Jianjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6357900/
https://www.ncbi.nlm.nih.gov/pubmed/30708325
http://dx.doi.org/10.1016/j.redox.2019.101120