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Impairment of Dendrodendritic Inhibition in the Olfactory Bulb of APP/PS1 Mice

Olfactory dysfunction is an early event in Alzheimer’s disease (AD). However, the mechanism underlying the AD-related changes in the olfactory bulb (OB) remains unknown. Granule cells (GCs) in the OB regulate the activity of mitral cells (MCs) through reciprocal dendrodendritic synapses, which is cr...

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Detalles Bibliográficos
Autores principales: Li, Weiyun, Li, Shanshan, Shen, Lianghua, Wang, Junbo, Wu, Xuewei, Li, Jing, Tu, Chunlong, Ye, Xuesong, Ling, Shucai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6357935/
https://www.ncbi.nlm.nih.gov/pubmed/30740049
http://dx.doi.org/10.3389/fnagi.2019.00002