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Impairment of Dendrodendritic Inhibition in the Olfactory Bulb of APP/PS1 Mice
Olfactory dysfunction is an early event in Alzheimer’s disease (AD). However, the mechanism underlying the AD-related changes in the olfactory bulb (OB) remains unknown. Granule cells (GCs) in the OB regulate the activity of mitral cells (MCs) through reciprocal dendrodendritic synapses, which is cr...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6357935/ https://www.ncbi.nlm.nih.gov/pubmed/30740049 http://dx.doi.org/10.3389/fnagi.2019.00002 |