Genetically Engineered T-Cells for Malignant Glioma: Overcoming the Barriers to Effective Immunotherapy

Malignant gliomas carry a dismal prognosis. Conventional treatment using chemo- and radiotherapy has limited efficacy with adverse events. Therapy with genetically engineered T-cells, such as chimeric antigen receptor (CAR) T-cells, may represent a promising approach to improve patient outcomes owin...

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Detalles Bibliográficos
Autores principales: Chuntova, Pavlina, Downey, Kira M., Hegde, Bindu, Almeida, Neil D., Okada, Hideho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6357938/
https://www.ncbi.nlm.nih.gov/pubmed/30740109
http://dx.doi.org/10.3389/fimmu.2018.03062

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6357938/
https://www.ncbi.nlm.nih.gov/pubmed/30740109
http://dx.doi.org/10.3389/fimmu.2018.03062

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