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Transition from a meiotic to a somatic-like DNA damage response during the pachytene stage in mouse meiosis

Homologous recombination (HR) is the principal mechanism of DNA repair acting during meiosis and is fundamental for the segregation of chromosomes and the increase of genetic diversity. Nevertheless, non-homologous end joining (NHEJ) mechanisms can also act during meiosis, mainly in response to exog...

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Detalles Bibliográficos
Autores principales: Enguita-Marruedo, Andrea, Martín-Ruiz, Marta, García, Eva, Gil-Fernández, Ana, Parra, María Teresa, Viera, Alberto, Rufas, Julio S., Page, Jesús
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6358097/
https://www.ncbi.nlm.nih.gov/pubmed/30668564
http://dx.doi.org/10.1371/journal.pgen.1007439