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Multiple roles of the non-structural protein 3 (nsP3) alphavirus unique domain (AUD) during Chikungunya virus genome replication and transcription

Chikungunya virus (CHIKV) is a re-emerging Alphavirus causing fever, joint pain, skin rash, arthralgia, and occasionally death. Antiviral therapies and/or effective vaccines are urgently required. CHIKV biology is poorly understood, in particular the functions of the non-structural protein 3 (nsP3)....

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Detalles Bibliográficos
Autores principales: Gao, Yanni, Goonawardane, Niluka, Ward, Joseph, Tuplin, Andrew, Harris, Mark
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6358111/
https://www.ncbi.nlm.nih.gov/pubmed/30668592
http://dx.doi.org/10.1371/journal.ppat.1007239