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Darunavir Population Pharmacokinetic Model Based on HIV Outpatient Data

BACKGROUND: Darunavir is a second-generation protease inhibitor and is registered for the treatment of HIV-1 infection. The aim of this study was to develop and validate a darunavir population pharmacokinetic model based on data from daily practice. METHODS: Data sets were obtained from 2 hospitals:...

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Detalles Bibliográficos
Autores principales: Daskapan, Alper, Tran, Quynh T.D., Cattaneo, Dario, Gervasoni, Cristina, Resnati, Chiara, Stienstra, Ymkje, Bierman, Wouter F.W., Kosterink, Jos G. W., van der Werf, Tjip S., Proost, Johannes H., Alffenaar, Jan-Willem C., Touw, Daniel J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Therapeutic Drug Monitoring 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6358182/
https://www.ncbi.nlm.nih.gov/pubmed/30489547
http://dx.doi.org/10.1097/FTD.0000000000000576