Quantification of Thiopurine Nucleotides in Erythrocytes and Clinical Application to Pediatric Acute Lymphoblastic Leukemia

BACKGROUND: Concentrations of 6-thioguanine (6TG) nucleotides and 6-methylmercaptopurine (6MMP) nucleotides in RBCs were measured using liquid chromatography-tandem mass spectrometry (LC-MS/MS). This assay was validated for clinical use and was applied to blood samples from patients taking mercaptop...

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Detalles Bibliográficos
Autores principales: Moon, Soo Young, Lim, Ji-Hyun, Kim, Eun-Hee, Nam, Youngwon, Yu, Kyung-Sang, Hong, Kyung Taek, Choi, Jung Yoon, Hong, Che Ry, Kim, Hyery, Kang, Hyoung Jin, Shin, Hee Young, Lee, Kyunghoon, Song, Junghan, Lee, Soo-Youn, Song, Sang Hoon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Therapeutic Drug Monitoring 2019
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6358190/
https://www.ncbi.nlm.nih.gov/pubmed/30507626
http://dx.doi.org/10.1097/FTD.0000000000000575

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6358190/
https://www.ncbi.nlm.nih.gov/pubmed/30507626
http://dx.doi.org/10.1097/FTD.0000000000000575

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