Efficacy and Safety of Tenofovir Disoproxil Fumarate Versus Low-Dose Stavudine Over 96 Weeks: A Multicountry Randomized, Noninferiority Trial

BACKGROUND: Reducing doses of antiretroviral drugs, including stavudine (d4T), may lower toxicity, while preserving efficacy. There are substantial concerns about renal and bone toxicities of tenofovir disoproxil fumarate (TDF). SETTING: HIV-1–infected treatment-naive adults in India, South Africa,...

Descripción completa

Detalles Bibliográficos
Autores principales: Venter, Willem Daniel Francois, Kambugu, Andrew, Chersich, Matthew F., Becker, Stephen, Hill, Andrew, Arulappan, Natasha, Moorhouse, Michelle, Majam, Mohammed, Akpomiemie, Godspower, Sokhela, Simiso, Poongulali, Selvamuthu, Feldman, Charles, Duncombe, Chris, Ripin, David H. Brown, Vos, Alinda, Kumarasamy, Nagalingeswaran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: JAIDS Journal of Acquired Immune Deficiency Syndromes 2019
Materias:
Clinical Science
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6358196/
https://www.ncbi.nlm.nih.gov/pubmed/30640204
http://dx.doi.org/10.1097/QAI.0000000000001908

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6358196/
https://www.ncbi.nlm.nih.gov/pubmed/30640204
http://dx.doi.org/10.1097/QAI.0000000000001908

Ejemplares similares