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Molecular safeguarding of CRISPR gene drive experiments

CRISPR-based homing gene drives have sparked both enthusiasm and deep concerns due to their potential for genetically altering entire species. This raises the question about our ability to prevent the unintended spread of such drives from the laboratory into a natural population. Here, we experiment...

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Detalles Bibliográficos
Autores principales: Champer, Jackson, Chung, Joan, Lee, Yoo Lim, Liu, Chen, Yang, Emily, Wen, Zhaoxin, Clark, Andrew G, Messer, Philipp W
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6358215/
https://www.ncbi.nlm.nih.gov/pubmed/30666960
http://dx.doi.org/10.7554/eLife.41439