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Factors affecting template switch recombination associated with restarted DNA replication

Homologous recombination helps ensure the timely completion of genome duplication by restarting collapsed replication forks. However, this beneficial function is not without risk as replication restarted by homologous recombination is prone to template switching (TS) that can generate deleterious ge...

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Detalles Bibliográficos
Autores principales: Jalan, Manisha, Oehler, Judith, Morrow, Carl A, Osman, Fekret, Whitby, Matthew C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6358216/
https://www.ncbi.nlm.nih.gov/pubmed/30667359
http://dx.doi.org/10.7554/eLife.41697