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Description of a Novel Phosphodiesterase (PDE)-3 Inhibitor Protecting Mice From Ischemic Stroke Independent From Platelet Function

BACKGROUND AND PURPOSE—: Acetylsalicylic acid and clopidogrel are the 2 main antithrombotic drugs for secondary prevention in patients with ischemic stroke (IS) without indication for anticoagulation. Because of their limited efficacy and potential side effects, novel antiplatelet agents are urgentl...

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Detalles Bibliográficos
Autores principales: Bieber, Michael, Schuhmann, Michael K., Volz, Julia, Kumar, Gangasani Jagadeesh, Vaidya, Jayathirtha Rao, Nieswandt, Bernhard, Pham, Mirko, Stoll, Guido, Kleinschnitz, Christoph, Kraft, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6358218/
https://www.ncbi.nlm.nih.gov/pubmed/30566040
http://dx.doi.org/10.1161/STROKEAHA.118.023664