Cargando…

Employing Dietary Comparators to Perform Risk Assessments for Anti-Androgens Without Using Animal Data

This study investigated the use of androgen receptor (AR) reporter gene assay data in a non-animal exposure-led risk assessment in which in vitro anti-androgenic activity and exposure data were put into context using a naturally occurring comparator substance with a history of dietary consumption. F...

Descripción completa

Detalles Bibliográficos
Autores principales: Dent, Matthew P, Li, Hequn, Carmichael, Paul L, Martin, Francis L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6358230/
https://www.ncbi.nlm.nih.gov/pubmed/30247711
http://dx.doi.org/10.1093/toxsci/kfy245