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Hepatic transcriptome analysis from HFD-fed mice defines a long noncoding RNA regulating cellular cholesterol levels

To elucidate the transcriptomic changes of long noncoding RNAs (lncRNAs) in high-fat diet (HFD)-fed mice, we defined their hepatic transcriptome by RNA sequencing. Aberrant expression of 37 representative lncRNAs and 254 protein-coding RNAs was observed in the livers of HFD-fed mice with insulin res...

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Detalles Bibliográficos
Autores principales: Chen, Qian, Xiong, Chaoliang, Jia, Kunyun, Jin, Jing, Li, Ziyang, Huang, Yazhou, Liu, Yewen, Wang, Lingling, Luo, Haitao, Li, Haiyan, Meng, Qing H., Li, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Biochemistry and Molecular Biology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6358296/
https://www.ncbi.nlm.nih.gov/pubmed/30504232
http://dx.doi.org/10.1194/jlr.M086215