VPS34 complexes from a structural perspective

VPS34 phosphorylates phosphatidylinositol to produce PtdIns3P and is the progenitor of the phosphoinositide 3-kinase (PI3K) family. VPS34 has a simpler domain organization than class I PI3Ks, which belies the complexity of its quaternary organization, with the enzyme always functioning within larger...

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Detalles Bibliográficos
Autores principales: Ohashi, Yohei, Tremel, Shirley, Williams, Roger L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Biochemistry and Molecular Biology 2019
Materias:
Thematic Review Series: The Role of Phosphoinositides in Signaling and Disease
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6358306/
https://www.ncbi.nlm.nih.gov/pubmed/30397185
http://dx.doi.org/10.1194/jlr.R089490

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6358306/
https://www.ncbi.nlm.nih.gov/pubmed/30397185
http://dx.doi.org/10.1194/jlr.R089490

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