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Melatonin for the treatment of gastroesophageal reflux disease; protocol for a systematic review and meta-analysis
BACKGROUND: Melatonin generated in the gastrointestinal tract has mucosal protective effect with inhibiting gastric acid secretion, while increasing gastrin release, which in turn stimulates the contractility of lower esophageal sphincter. Gastroesophageal reflux disease (GERD) is also known to have...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wolters Kluwer Health
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6358381/ https://www.ncbi.nlm.nih.gov/pubmed/30681611 http://dx.doi.org/10.1097/MD.0000000000014241 |