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Discovery of common and rare genetic risk variants for colorectal cancer

To further dissect the genetic architecture of colorectal cancer (CRC), we performed whole-genome sequencing of 1,439 cases and 720 controls, imputed discovered sequence variants and Haplotype Reference Consortium panel variants into genome-wide association study data, and tested for association in...

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Detalles Bibliográficos
Autores principales: Huyghe, Jeroen R, Bien, Stephanie A, Harrison, Tabitha A, Kang, Hyun Min, Chen, Sai, Schmit, Stephanie L, Conti, David V, Qu, Conghui, Jeon, Jihyoun, Edlund, Christopher K, Greenside, Peyton, Wainberg, Michael, Schumacher, Fredrick R, Smith, Joshua D, Levine, David M, Nelson, Sarah C, Sinnott-Armstrong, Nasa A, Albanes, Demetrius, Alonso, M Henar, Anderson, Kristin, Arnau-Collell, Coral, Arndt, Volker, Bamia, Christina, Banbury, Barbara L, Baron, John A, Berndt, Sonja I, Bézieau, Stéphane, Bishop, D Timothy, Boehm, Juergen, Boeing, Heiner, Brenner, Hermann, Brezina, Stefanie, Buch, Stephan, Buchanan, Daniel D, Burnett-Hartman, Andrea, Butterbach, Katja, Caan, Bette J, Campbell, Peter T, Carlson, Christopher S, Castellví-Bel, Sergi, Chan, Andrew T, Chang-Claude, Jenny, Chanock, Stephen J, Chirlaque, Maria-Dolores, Cho, Sang Hee, Connolly, Charles M, Cross, Amanda J, Cuk, Katarina, Curtis, Keith R, de la Chapelle, Albert, Doheny, Kimberly F, Duggan, David, Easton, Douglas F, Elias, Sjoerd G, Elliott, Faye, English, Dallas R, Feskens, Edith JM, Figueiredo, Jane C, Fischer, Rocky, FitzGerald, Liesel M, Forman, David, Gala, Manish, Gallinger, Steven, Gauderman, W James, Giles, Graham G, Gillanders, Elizabeth, Gong, Jian, Goodman, Phyllis J, Grady, William M, Grove, John S, Gsur, Andrea, Gunter, Marc J, Haile, Robert W, Hampe, Jochen, Hampel, Heather, Harlid, Sophia, Hayes, Richard B, Hofer, Philipp, Hoffmeister, Michael, Hopper, John L, Hsu, Wan-Ling, Huang, Wen-Yi, Hudson, Thomas J, Hunter, David J, Ibañez-Sanz, Gemma, Idos, Gregory E, Ingersoll, Roxann, Jackson, Rebecca D, Jacobs, Eric J, Jenkins, Mark A, Joshi, Amit D, Joshu, Corinne E, Keku, Temitope O, Key, Timothy J, Kim, Hyeong Rok, Kobayashi, Emiko, Kolonel, Laurence N, Kooperberg, Charles, Kühn, Tilman, Küry, Sébastien, Kweon, Sun-Seog, Larsson, Susanna C, Laurie, Cecelia A, Le Marchand, Loic, Leal, Suzanne M, Lee, Soo Chin, Lejbkowicz, Flavio, Lemire, Mathieu, Li, Christopher I, Li, Li, Lieb, Wolfgang, Lin, Yi, Lindblom, Annika, Lindor, Noralane M, Ling, Hua, Louie, Tin L, Männistö, Satu, Markowitz, Sanford D, Martín, Vicente, Masala, Giovanna, McNeil, Caroline E, Melas, Marilena, Milne, Roger L, Moreno, Lorena, Murphy, Neil, Myte, Robin, Naccarati, Alessio, Newcomb, Polly A, Offit, Kenneth, Ogino, Shuji, Onland-Moret, N Charlotte, Pardini, Barbara, Parfrey, Patrick S, Pearlman, Rachel, Perduca, Vittorio, Pharoah, Paul D P, Pinchev, Mila, Platz, Elizabeth A, Prentice, Ross L, Pugh, Elizabeth, Raskin, Leon, Rennert, Gad, Rennert, Hedy S, Riboli, Elio, Rodríguez-Barranco, Miguel, Romm, Jane, Sakoda, Lori C, Schafmayer, Clemens, Schoen, Robert E, Seminara, Daniela, Shah, Mitul, Shelford, Tameka, Shin, Min-Ho, Shulman, Katerina, Sieri, Sabina, Slattery, Martha L, Southey, Melissa C, Stadler, Zsofia K, Stegmaier, Christa, Su, Yu-Ru, Tangen, Catherine M, Thibodeau, Stephen N, Thomas, Duncan C, Thomas, Sushma S, Toland, Amanda E, Trichopoulou, Antonia, Ulrich, Cornelia M, Van Den Berg, David J, van Duijnhoven, Franzel JB, Van Guelpen, Bethany, van Kranen, Henk, Vijai, Joseph, Visvanathan, Kala, Vodicka, Pavel, Vodickova, Ludmila, Vymetalkova, Veronika, Weigl, Korbinian, Weinstein, Stephanie J, White, Emily, Win, Aung Ko, Wolf, C Roland, Wolk, Alicja, Woods, Michael O, Wu, Anna H, Zaidi, Syed H, Zanke, Brent W, Zhang, Qing, Zheng, Wei, Scacheri, Peter C, Potter, John D, Bassik, Michael C, Kundaje, Anshul, Casey, Graham, Moreno, Victor, Abecasis, Goncalo R, Nickerson, Deborah A, Gruber, Stephen B, Hsu, Li, Peters, Ulrike
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6358437/
https://www.ncbi.nlm.nih.gov/pubmed/30510241
http://dx.doi.org/10.1038/s41588-018-0286-6