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Repurposing large health insurance claims data to estimate genetic and environmental contributions in 560 phenotypes

We analyzed a large health insurance dataset to assess the genetic and environmental contributions of 560 disease-related phenotypes in 56,396 twin pairs and 724,513 sibling pairs out of 44,859,462 individuals that live in the United States. We estimated the contribution of environmental risk factor...

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Detalles Bibliográficos
Autores principales: Lakhani, Chirag M, Tierney, Braden T, Manrai, Arjun K, Yang, Jian, Visscher, Peter M, Patel, Chirag J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6358510/
https://www.ncbi.nlm.nih.gov/pubmed/30643253
http://dx.doi.org/10.1038/s41588-018-0313-7