Hypothalamic POMC or MC4R deficiency impairs counterregulatory responses to hypoglycemia in mice

OBJECTIVE: Life-threatening hypoglycemia is a major limiting factor in the management of diabetes. While it is known that counterregulatory responses to hypoglycemia are impaired in diabetes, molecular mechanisms underlying the reduced responses remain unclear. Given the established roles of the hyp...

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Detalles Bibliográficos
Autores principales: Tooke, Benjamin P., Yu, Hui, Adams, Jessica M., Jones, Graham L., Sutton-Kennedy, Talisha, Mundada, Lakshmi, Qi, Nathan R., Low, Malcolm J., Chhabra, Kavaljit H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6358536/
https://www.ncbi.nlm.nih.gov/pubmed/30503832
http://dx.doi.org/10.1016/j.molmet.2018.11.004

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6358536/
https://www.ncbi.nlm.nih.gov/pubmed/30503832
http://dx.doi.org/10.1016/j.molmet.2018.11.004

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