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Deletion of myeloid IRS2 enhances adipose tissue sympathetic nerve function and limits obesity

OBJECTIVE: Sympathetic nervous system and immune cell interactions play key roles in the regulation of metabolism. For example, recent convergent studies have shown that macrophages regulate obesity through brown adipose tissue (BAT) activation and beiging of white adipose tissue (WAT) via effects u...

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Detalles Bibliográficos
Autores principales: Rached, Marie-Therese, Millership, Steven J., Pedroni, Silvia M.A., Choudhury, Agharul I., Costa, Ana S.H., Hardy, Darran G., Glegola, Justyna A., Irvine, Elaine E., Selman, Colin, Woodberry, Megan C., Yadav, Vijay K., Khadayate, Sanjay, Vidal-Puig, Antonio, Virtue, Samuel, Frezza, Christian, Withers, Dominic J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6358539/
https://www.ncbi.nlm.nih.gov/pubmed/30553769
http://dx.doi.org/10.1016/j.molmet.2018.11.010