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Hepatic c-Jun regulates glucose metabolism via FGF21 and modulates body temperature through the neural signals
OBJECTIVE: c-Jun, a prominent member of the activator protein 1 (AP-1) family, is involved in various physiology processes such as cell death and survival. However, a role of hepatic c-Jun in the whole-body metabolism is poorly understood. METHODS: We generated liver-specific c-Jun knock-out (c-jun(...
Autores principales: | , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6358569/ https://www.ncbi.nlm.nih.gov/pubmed/30579932 http://dx.doi.org/10.1016/j.molmet.2018.12.003 |