Hepatic c-Jun regulates glucose metabolism via FGF21 and modulates body temperature through the neural signals

OBJECTIVE: c-Jun, a prominent member of the activator protein 1 (AP-1) family, is involved in various physiology processes such as cell death and survival. However, a role of hepatic c-Jun in the whole-body metabolism is poorly understood. METHODS: We generated liver-specific c-Jun knock-out (c-jun(...

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Detalles Bibliográficos
Autores principales: Xiao, Fei, Guo, Yajie, Deng, Jiali, Yuan, Feixiang, Xiao, Yuzhong, Hui, Lijian, Li, Yu, Hu, Zhimin, Zhou, Yuncai, Li, Kai, Han, Xiao, Fang, Qichen, Jia, Weiping, Chen, Yan, Ying, Hao, Zhai, Qiwei, Chen, Shanghai, Guo, Feifan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6358569/
https://www.ncbi.nlm.nih.gov/pubmed/30579932
http://dx.doi.org/10.1016/j.molmet.2018.12.003

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