A dual Ucp1 reporter mouse model for imaging and quantitation of brown and brite fat recruitment
OBJECTIVES: Brown adipose tissue (BAT) dissipates nutritional energy as heat through uncoupling protein 1 (UCP1). The discovery of functional BAT in healthy adult humans has promoted the search for pharmacological interventions to recruit and activate brown fat as a treatment of obesity and diabetes...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6358570/ https://www.ncbi.nlm.nih.gov/pubmed/30580967 http://dx.doi.org/10.1016/j.molmet.2018.11.009 |