A dual Ucp1 reporter mouse model for imaging and quantitation of brown and brite fat recruitment

OBJECTIVES: Brown adipose tissue (BAT) dissipates nutritional energy as heat through uncoupling protein 1 (UCP1). The discovery of functional BAT in healthy adult humans has promoted the search for pharmacological interventions to recruit and activate brown fat as a treatment of obesity and diabetes...

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Detalles Bibliográficos
Autores principales: Wang, Hui, Willershäuser, Monja, Karlas, Angelos, Gorpas, Dimitris, Reber, Josefine, Ntziachristos, Vasilis, Maurer, Stefanie, Fromme, Tobias, Li, Yongguo, Klingenspor, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6358570/
https://www.ncbi.nlm.nih.gov/pubmed/30580967
http://dx.doi.org/10.1016/j.molmet.2018.11.009