NK Cells Activated through Antibody-Dependent Cell Cytotoxicity and Armed with Degranulation/IFN-γ Production Suppress Antibody-dependent Enhancement of Dengue Viral Infection

Antibody (Ab)-dependent enhancement (ADE) is a hypothesized mechanism of increased disease severity during secondary dengue virus (DENV) infection. This study investigates Ab-dependent cell cytotoxicity (ADCC) in counteracting ADE. In our system, DENV and DENV-immune sera were added to peripheral bl...

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Detalles Bibliográficos
Autores principales: Sun, Peifang, Williams, Maya, Nagabhushana, Nishith, Jani, Vihasi, Defang, Gabriel, Morrison, Brian J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6358599/
https://www.ncbi.nlm.nih.gov/pubmed/30710094
http://dx.doi.org/10.1038/s41598-018-36972-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6358599/
https://www.ncbi.nlm.nih.gov/pubmed/30710094
http://dx.doi.org/10.1038/s41598-018-36972-2

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