The catalytic activity and secretion of zebrafish RNases are essential for their in vivo function in motor neurons and vasculature

Angiogenin (hANG), a member of the Ribonuclease A superfamily has angiogenic, neurotrophic and neuroprotective activities. Mutations in hANG have been found in patients with Amyotrophic lateral sclerosis (ALS). The zebrafish (Danio rerio) rnasel-1, 2 and 3 are orthologues of hANG and of these only R...

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Detalles Bibliográficos
Autores principales: Ferguson, Ross, Holloway, Daniel E., Chandrasekhar, Anand, Acharya, K. Ravi, Subramanian, Vasanta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6358602/
https://www.ncbi.nlm.nih.gov/pubmed/30710110
http://dx.doi.org/10.1038/s41598-018-37140-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6358602/
https://www.ncbi.nlm.nih.gov/pubmed/30710110
http://dx.doi.org/10.1038/s41598-018-37140-2

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