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Vasoactive intestinal peptide controls the suprachiasmatic circadian clock network via ERK1/2 and DUSP4 signalling

The suprachiasmatic nucleus (SCN) co-ordinates circadian behaviour and physiology in mammals. Its cell-autonomous circadian oscillations pivot around a well characterised transcriptional/translational feedback loop (TTFL), whilst the SCN circuit as a whole is synchronised to solar time by its retino...

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Detalles Bibliográficos
Autores principales: Hamnett, Ryan, Crosby, Priya, Chesham, Johanna E., Hastings, Michael H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6358603/
https://www.ncbi.nlm.nih.gov/pubmed/30710088
http://dx.doi.org/10.1038/s41467-019-08427-3