iPSC model of CHRFAM7A effect on α7 nicotinic acetylcholine receptor function in the human context

The α7 nicotinic acetylcholine receptor (α7nAChR) has been a promising target for diseases affecting cognition and higher cortical functions; however, the effect observed in animal models failed to translate into human clinical trials identifying a translational gap. CHRFAM7A is a human-specific fus...

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Detalles Bibliográficos
Autores principales: Ihnatovych, Ivanna, Nayak, Tapan K., Ouf, Aya, Sule, Norbert, Birkaya, Barbara, Chaves, Lee, Auerbach, Anthony, Szigeti, Kinga
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6358606/
https://www.ncbi.nlm.nih.gov/pubmed/30710073
http://dx.doi.org/10.1038/s41398-019-0375-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6358606/
https://www.ncbi.nlm.nih.gov/pubmed/30710073
http://dx.doi.org/10.1038/s41398-019-0375-z

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