Risk gene-set and pathways in 22q11.2 deletion-related schizophrenia: a genealogical molecular approach

The 22q11.2 deletion is a strong, but insufficient, “first hit” genetic risk factor for schizophrenia (SZ). We attempted to identify “second hits” from the entire genome in a unique multiplex 22q11.2 deletion syndrome (DS) family. Bioinformatic analysis of whole-exome sequencing and comparative-geno...

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Detalles Bibliográficos
Autores principales: Michaelovsky, Elena, Carmel, Miri, Frisch, Amos, Salmon-Divon, Mali, Pasmanik-Chor, Metsada, Weizman, Abraham, Gothelf, Doron
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6358611/
https://www.ncbi.nlm.nih.gov/pubmed/30710087
http://dx.doi.org/10.1038/s41398-018-0354-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6358611/
https://www.ncbi.nlm.nih.gov/pubmed/30710087
http://dx.doi.org/10.1038/s41398-018-0354-9

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