Dehydration and insulinopenia are necessary and sufficient for euglycemic ketoacidosis in SGLT2 inhibitor-treated rats

Sodium-glucose transport protein 2 (SGLT2) inhibitors are a class of anti-diabetic agents; however, concerns have been raised about their potential to induce euglycemic ketoacidosis and to increase both glucose production and glucagon secretion. The mechanisms behind these alterations are unknown. H...

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Detalles Bibliográficos
Autores principales: Perry, Rachel J., Rabin-Court, Aviva, Song, Joongyu D., Cardone, Rebecca L., Wang, Yongliang, Kibbey, Richard G., Shulman, Gerald I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6358621/
https://www.ncbi.nlm.nih.gov/pubmed/30710078
http://dx.doi.org/10.1038/s41467-019-08466-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6358621/
https://www.ncbi.nlm.nih.gov/pubmed/30710078
http://dx.doi.org/10.1038/s41467-019-08466-w

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