Multistate design of influenza antibodies improves affinity and breadth against seasonal viruses

Influenza is a yearly threat to global public health. Rapid changes in influenza surface proteins resulting from antigenic drift and shift events make it difficult to readily identify antibodies with broadly neutralizing activity against different influenza subtypes with high frequency, specifically...

Descripción completa

Detalles Bibliográficos
Autores principales: Sevy, Alexander M., Wu, Nicholas C., Gilchuk, Iuliia M., Parrish, Erica H., Burger, Sebastian, Yousif, Dina, Nagel, Marcus B. M., Schey, Kevin L., Wilson, Ian A., Crowe, James E., Meiler, Jens
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2019
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6358683/
https://www.ncbi.nlm.nih.gov/pubmed/30642961
http://dx.doi.org/10.1073/pnas.1806004116

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6358683/
https://www.ncbi.nlm.nih.gov/pubmed/30642961
http://dx.doi.org/10.1073/pnas.1806004116

Ejemplares similares