Structure of the lipoprotein lipase–GPIHBP1 complex that mediates plasma triglyceride hydrolysis

Lipoprotein lipase (LPL) is responsible for the intravascular processing of triglyceride-rich lipoproteins. The LPL within capillaries is bound to GPIHBP1, an endothelial cell protein with a three-fingered LU domain and an N-terminal intrinsically disordered acidic domain. Loss-of-function mutations...

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Detalles Bibliográficos
Autores principales: Birrane, Gabriel, Beigneux, Anne P., Dwyer, Brian, Strack-Logue, Bettina, Kristensen, Kristian Kølby, Francone, Omar L., Fong, Loren G., Mertens, Haydyn D. T., Pan, Clark Q., Ploug, Michael, Young, Stephen G., Meiyappan, Muthuraman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2019
Materias:
PNAS Plus
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6358717/
https://www.ncbi.nlm.nih.gov/pubmed/30559189
http://dx.doi.org/10.1073/pnas.1817984116

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6358717/
https://www.ncbi.nlm.nih.gov/pubmed/30559189
http://dx.doi.org/10.1073/pnas.1817984116

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