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PCSK9 is Expressed in Human Visceral Adipose Tissue and Regulated by Insulin and Cardiac Natriuretic Peptides

Proprotein convertase subtilisin/kexin type 9 (PCSK9) binds to and degrades the low-density lipoprotein receptor (LDLR), contributing to hypercholesterolemia. Adipose tissue plays a role in lipoprotein metabolism, but there are almost no data about PCSK9 and LDLR regulation in human adipocytes. We s...

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Detalles Bibliográficos
Autores principales: Bordicchia, Marica, Spannella, Francesco, Ferretti, Gianna, Bacchetti, Tiziana, Vignini, Arianna, Di Pentima, Chiara, Mazzanti, Laura, Sarzani, Riccardo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6358804/
https://www.ncbi.nlm.nih.gov/pubmed/30634533
http://dx.doi.org/10.3390/ijms20020245